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Name
Jakubowski, Hieronim
Scientific title
prof. dr hab.
ORCID
0000-0001-5845-4409
Publications
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7 results
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2023 - 2024
7
Author
Jakubowski, Hieronim
7
Witucki, Łukasz
5
Borowczyk, Kamila
1
Pawlak, Piotr
1
Suszyńska-Zajczyk, Joanna
1
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Subject
autophagy
homocysteine thiolactone
5
H4K20me1
3
mTOR
3
Phf8
3
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7
Type
Journal article
7
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1 - 7 of 7
Publication
2023
Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
Witucki, Łukasz
Jakubowski, Hieronim
5
5
Publication
2023
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice
Witucki, Łukasz
Jakubowski, Hieronim
17
17
Publication
2023
Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice
Witucki, Łukasz
Jakubowski, Hieronim
5
5
Publication
2024
Association of GLOD4 with Alzheimer’s Disease in Humans and Mice
Utyro, Olga
Włoczkowska-Łapińska, Olga
Jakubowski, Hieronim
13
13
Publication
2024
Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
Jakubowski, Hieronim
24
24
Publication
2024
Homocysteine metabolites inhibit autophagy by upregulating miR-21-5p, miR-155-5p, miR-216-5p, and miR-320c-3p in human vascular endothelial cells
Witucki, Łukasz
Jakubowski, Hieronim
31
31
Publication
2023
Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease
Witucki, Łukasz
Borowczyk, Kamila
Suszyńska-Zajczyk, Joanna
Warzych-Plejer, Ewelina
Pawlak, Piotr
Jakubowski, Hieronim
15
15