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Name
Jakubowski, Hieronim
Scientific title
prof. dr hab.
ORCID
0000-0001-5845-4409
Publications
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7 results
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2023 - 2025
7
Author
Jakubowski, Hieronim
7
Witucki, Łukasz
5
Borowczyk, Kamila
1
Pawlak, Piotr
1
Suszyńska-Zajczyk, Joanna
1
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Subject
homocysteine thiolactone
autophagy
5
H4K20me1
3
mTOR
3
Phf8
3
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7
Type
Journal article
7
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1 - 7 of 7
Publication
2024
Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
Jakubowski, Hieronim
24
24
Publication
2024
The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1
Jakubowski, Hieronim
11
11
Publication
2023
Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease
Witucki, Łukasz
Borowczyk, Kamila
Suszyńska-Zajczyk, Joanna
Warzych-Plejer, Ewelina
Pawlak, Piotr
Jakubowski, Hieronim
15
15
Publication
2023
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice
Witucki, Łukasz
Jakubowski, Hieronim
17
17
Publication
2023
Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice
Witucki, Łukasz
Jakubowski, Hieronim
4
4
Publication
2025
Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease
Jakubowski, Hieronim
Witucki, Łukasz
10
10
Publication
2023
Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
Witucki, Łukasz
Jakubowski, Hieronim
5
5