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Name
Jakubowski, Hieronim
Scientific title
prof. dr hab.
ORCID
0000-0001-5845-4409
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7 results
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2023 - 2025
7
Author
Jakubowski, Hieronim
7
Witucki, Łukasz
5
Borowczyk, Kamila
1
Pawlak, Piotr
1
Suszyńska-Zajczyk, Joanna
1
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Subject
homocysteine thiolactone
autophagy
5
H4K20me1
3
mTOR
3
Phf8
3
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7
Type
Journal article
7
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1 - 7 of 7
Publication
2023
Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice
Witucki, Łukasz
Jakubowski, Hieronim
5
5
Publication
2023
Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
Witucki, Łukasz
Jakubowski, Hieronim
5
5
Publication
2024
Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
Jakubowski, Hieronim
24
24
Publication
2024
The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1
Jakubowski, Hieronim
11
11
Publication
2025
Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease
Jakubowski, Hieronim
Witucki, Łukasz
10
10
Publication
2023
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice
Witucki, Łukasz
Jakubowski, Hieronim
17
17
Publication
2023
Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease
Witucki, Łukasz
Borowczyk, Kamila
Suszyńska-Zajczyk, Joanna
Warzych-Plejer, Ewelina
Pawlak, Piotr
Jakubowski, Hieronim
15
15