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Name
Witucki, Łukasz
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dr
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2023 - 2024
4
Author
Jakubowski, Hieronim
4
Witucki, Łukasz
4
Borowczyk, Kamila
1
Pawlak, Piotr
1
Suszyńska-Zajczyk, Joanna
1
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Subject
autophagy
H4K20me1
3
homocysteine thiolactone
3
Phf8
3
amyloid beta
2
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4
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Journal article
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Publication
2023
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice
Witucki, Łukasz
Jakubowski, Hieronim
12
12
Publication
2023
Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease
Witucki, Łukasz
Borowczyk, Kamila
Suszyńska-Zajczyk, Joanna
Warzych-Plejer, Ewelina
Pawlak, Piotr
Jakubowski, Hieronim
13
13
Publication
2024
Homocysteine metabolites inhibit autophagy by upregulating miR-21-5p, miR-155-5p, miR-216-5p, and miR-320c-3p in human vascular endothelial cells
Witucki, Łukasz
Jakubowski, Hieronim
21
21
Publication
2023
Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
Witucki, Łukasz
Jakubowski, Hieronim
2
2
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