Jakubowski, Hieronim

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Jakubowski, Hieronim

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prof. dr hab.

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0000-0001-5845-4409

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2017 - 20192

2020 - 202521

Jakubowski, Hieronim 19

Witucki, Łukasz 9

Hieronim Jakubowski 4

Bretes, Ewa 3

Perła-Kaján, Joanna 3

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autophagy 7

homocysteine thiolactone 7

Alzheimer’s disease 4

amyloid beta 3

cardiovascular disease 3

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2025
Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease
Jakubowski, Hieronim
Witucki, Łukasz
9 9
2022
COVID-19 and One-Carbon Metabolism
Perła-Kaján, Joanna
Jakubowski, Hieronim
4 4
Hydrolaza bleomycyny, metabolizm homocysteiny, epigenetyczna regulacja mTOR, autofagia i choroba Alzheimera
2023
Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
Witucki, Łukasz
Jakubowski, Hieronim
5 5
2024
Homocysteine metabolites impair the PHF8/H4K20me1/mTOR/autophagy pathway by upregulating the expression of histone demethylase PHF8‐targeting microRNAs in human vascular endothelial cells and mice
Witucki, Łukasz
Jakubowski, Hieronim
23 23
2024
Association of Metallic and Nonmetallic Elements with Fibrin Clot Properties and Ischemic Stroke
Jakubowski, Hieronim
Sikora, Marta
Bretes, Ewa
Perła-Kajan, Joanna
Utyro, Olga
Wojtasz, Izabela
Kaźmierski, Radosław
Frankowski, Marcin
Zioła-Frankowska, Anetta
20 20
2022
Czy badania prowadzone w Katedrze Biochemii i Biotechnologii pozwolą na identyfikację nowych czynników ryzyka choroby Alzheimera i chorób sercowo-naczyniowych?
Jakubowski, Hieronim
Zeyland, Joanna
4 4
2024
Diet-induced hyperhomocysteinemia causes sex-dependent deficiencies in offspring musculature and brain function
Suszyńska-Zajczyk, Joanna
Witucki, Łukasz
Perła-Kajan, Joanna
Jakubowski, Hieronim
13 13
2023
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice
Witucki, Łukasz
Jakubowski, Hieronim
17 17
2022
Cystathionine β‐synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice
Bretes, Ewa
Wróblewski, Jacek
Wyszczelska‐Rokiel, Monika
Jakubowski, Hieronim
18 18
2024
Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
Jakubowski, Hieronim
23 23
Odpowiedź autoimmunologiczna i liza skrzepów fibrynowych w chorobach sercowo-naczyniowych
2023
Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice
Witucki, Łukasz
Jakubowski, Hieronim
3 3
2024
Homocysteine thiolactone and other sulfur-containing amino acid metabolites are associated with fibrin clot properties and the risk of ischemic stroke
Sikora, Marta
Bretes, Ewa
Perła-Kaján, Joanna
Utyro, Olga
Borowczyk, Kamila
Piechocka, Justyna
Głowacki, Rafał
Wojtasz, Izabela
Kaźmierski, Radosław
Jakubowski, Hieronim
17 17
2022
Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease
Sikora, Marta
Skrzydlewski, Paweł
Perła-Kaján, Joanna
Jakubowski, Hieronim
5 5
Mechanizmy epigenetycznych modyfikacji histonów w hiperhomocysteinemii
2022
Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease
Witucki, Łukasz
Kurpik, Monika
Jakubowski, Hieronim
Szulc, Michał
Łukasz Mikołajczak, Przemysław
Jodynis-Liebert, Jadwiga
Kujawska, Małgorzata
7 7
2024
The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1
Jakubowski, Hieronim
11 11
2023
Proteomic Exploration of Paraoxonase 1 Function in Health and Disease
Jakubowski, Hieronim
14 14
2024
Association of GLOD4 with Alzheimer’s Disease in Humans and Mice
Utyro, Olga
Włoczkowska-Łapińska, Olga
Jakubowski, Hieronim
12 12

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Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease

COVID-19 and One-Carbon Metabolism

Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice

Homocysteine metabolites impair the PHF8/H4K20me1/mTOR/autophagy pathway by upregulating the expression of histone demethylase PHF8‐targeting microRNAs in human vascular endothelial cells and mice

Association of Metallic and Nonmetallic Elements with Fibrin Clot Properties and Ischemic Stroke

Czy badania prowadzone w Katedrze Biochemii i Biotechnologii pozwolą na identyfikację nowych czynników ryzyka choroby Alzheimera i chorób sercowo-naczyniowych?

Diet-induced hyperhomocysteinemia causes sex-dependent deficiencies in offspring musculature and brain function

Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice

Cystathionine β‐synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice

Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease

Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice

Homocysteine thiolactone and other sulfur-containing amino acid metabolites are associated with fibrin clot properties and the risk of ischemic stroke

Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease

Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease

The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1

Proteomic Exploration of Paraoxonase 1 Function in Health and Disease

Association of GLOD4 with Alzheimer’s Disease in Humans and Mice