Jakubowski, Hieronim

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Jakubowski, Hieronim

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prof. dr hab.

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0000-0001-5845-4409

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Perła-Kaján, Joanna 3

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autophagy 7

homocysteine thiolactone 7

Alzheimer’s disease 4

amyloid beta 3

cardiovascular disease 3

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2022
Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease
Witucki, Łukasz
Kurpik, Monika
Jakubowski, Hieronim
Szulc, Michał
Łukasz Mikołajczak, Przemysław
Jodynis-Liebert, Jadwiga
Kujawska, Małgorzata
7 7
2024
Association of GLOD4 with Alzheimer’s Disease in Humans and Mice
Utyro, Olga
Włoczkowska-Łapińska, Olga
Jakubowski, Hieronim
13 13
2023
Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice
Witucki, Łukasz
Jakubowski, Hieronim
5 5
Mechanizmy epigenetycznych modyfikacji histonów w hiperhomocysteinemii
2023
Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice
Witucki, Łukasz
Jakubowski, Hieronim
5 5
2024
Diet-induced hyperhomocysteinemia causes sex-dependent deficiencies in offspring musculature and brain function
Suszyńska-Zajczyk, Joanna
Witucki, Łukasz
Perła-Kajan, Joanna
Jakubowski, Hieronim
13 13
2024
Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease
Jakubowski, Hieronim
24 24
2022
Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease
Sikora, Marta
Skrzydlewski, Paweł
Perła-Kaján, Joanna
Jakubowski, Hieronim
5 5
Hydrolaza bleomycyny, metabolizm homocysteiny, epigenetyczna regulacja mTOR, autofagia i choroba Alzheimera
2022
COVID-19 and One-Carbon Metabolism
Perła-Kaján, Joanna
Jakubowski, Hieronim
4 4
2024
The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1
Jakubowski, Hieronim
11 11
2025
Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease
Jakubowski, Hieronim
Witucki, Łukasz
10 10
2024
Homocysteine metabolites inhibit autophagy by upregulating miR-21-5p, miR-155-5p, miR-216-5p, and miR-320c-3p in human vascular endothelial cells
Witucki, Łukasz
Jakubowski, Hieronim
31 31
Rola paraoksonazy 1 w chorobie Alzheimer'a.
2023
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice
Witucki, Łukasz
Jakubowski, Hieronim
17 17
Odpowiedź autoimmunologiczna i liza skrzepów fibrynowych w chorobach sercowo-naczyniowych
2024
Homocysteine thiolactone and other sulfur-containing amino acid metabolites are associated with fibrin clot properties and the risk of ischemic stroke
Sikora, Marta
Bretes, Ewa
Perła-Kaján, Joanna
Utyro, Olga
Borowczyk, Kamila
Piechocka, Justyna
Głowacki, Rafał
Wojtasz, Izabela
Kaźmierski, Radosław
Jakubowski, Hieronim
17 17
2023
Proteomic Exploration of Paraoxonase 1 Function in Health and Disease
Jakubowski, Hieronim
14 14
2023
Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease
Witucki, Łukasz
Borowczyk, Kamila
Suszyńska-Zajczyk, Joanna
Warzych-Plejer, Ewelina
Pawlak, Piotr
Jakubowski, Hieronim
15 15
2022
Czy badania prowadzone w Katedrze Biochemii i Biotechnologii pozwolą na identyfikację nowych czynników ryzyka choroby Alzheimera i chorób sercowo-naczyniowych?
Jakubowski, Hieronim
Zeyland, Joanna
5 5

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Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease

Association of GLOD4 with Alzheimer’s Disease in Humans and Mice

Homocysteine Metabolites Impair the PHF8/H4K20me1/mTOR/Autophagy Pathway by Upregulating the Expression of Histone Demethylase PHF8-targeting microRNAs in Human Vascular Endothelial Cells and Mice

Depletion of Paraoxonase 1 (Pon1) Dysregulates mTOR, Autophagy, and Accelerates Amyloid Beta Accumulation in Mice

Diet-induced hyperhomocysteinemia causes sex-dependent deficiencies in offspring musculature and brain function

Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer’s Disease

Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease

COVID-19 and One-Carbon Metabolism

The Molecular Bases of Anti-Oxidative and Anti-Inflammatory Properties of Paraoxonase 1

Homocysteine Metabolites, Endothelial Dysfunction, and Cardiovascular Disease

Homocysteine metabolites inhibit autophagy by upregulating miR-21-5p, miR-155-5p, miR-216-5p, and miR-320c-3p in human vascular endothelial cells

Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice

Homocysteine thiolactone and other sulfur-containing amino acid metabolites are associated with fibrin clot properties and the risk of ischemic stroke

Proteomic Exploration of Paraoxonase 1 Function in Health and Disease

Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer’s Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer’s Disease

Czy badania prowadzone w Katedrze Biochemii i Biotechnologii pozwolą na identyfikację nowych czynników ryzyka choroby Alzheimera i chorób sercowo-naczyniowych?