Immune status of piglets during the first week of life: Current knowledge, significance and assessment – a review

The immune system of neonate piglets differs from adult pigs in structure and competence. although piglets are born immunocompe tent, they are genuinely immunologically defenseless. to survive in the environment, piglets need passive protection provided by sow’s colostrum and milk when constantly exposed to numerous pathogens. early assessment of piglets’ immune status may enable rapid intervention in case of detection of any deficiencies or disorders. Moreover, awareness of the piglets’ immunocompetence and the level of maternally-derived antibodies (mda) may allow the creation of a proper vaccine schedule. hence, extending knowledge of prenatal ontogeny of the porcine immune system, the immune status of neonate piglets’ and the immunological components of porcine colostrum is crucial. since animal welfare has become a more critical element of animal production, new, non-invasive sampling methodologies are highly desirable for the evaluation of piglets’ immune status.