Effects of magnetic stimulation and kinesitherapy on inflammatory and nutritional parameters in hemodialysis patients: a pilot study

Purpose: The study evaluated the effects of low-frequency magnetic field and kinesitherapy on selected parameters of nutritional status and inflammation in patients with chronic kidney disease (CKD) undergoing hemodialysis.
Methods: The study included 25 hemodialysis patients with stage G5 CKD, divided into three groups: magnetic stimulation + kinesitherapy, kinesitherapy only, and a control group. Magnetic stimulation was applied three times a week for 12 weeks. Blood tests were performed to assess nutritional status (TP, ALB, TC, TG), inflammation (CRP) and liver enzymes AST and ALT.
Results: Before treatment, there were no statistically significant differences in TC (P = .675), TG (P = .861), ALT (P = .991), AST (P = .840), TP (P = .509), or ALB (P = .276). CRP values trended toward statistical significance (P = .069); the highest median was seen in Group 2 (10.50 mg/L). After therapy, there was a significant decrease in CRP levels in Group 2 (P =.013). Other parameters showed no significant changes. TC decreased in all groups, with the greatest decrease observed in the control group. TG levels varied among groups: they increased in Group 1, decreased in the control group, and remained stable in Group 2 (P = .245). AST and ALT stayed within normal limits. ALB levels slightly decreased in Groups 1 and 2, which, along with higher CRP, suggests an association with inflammation.
Conclusion: Some patients with advanced CKD on haemodialysis have elevated CRP levels and low albumin, which maysignal malnutrition. Both treatments can affect inflammatory and nutritional status.