Acute phase proteins in wildlife and their domesticated relatives

cris.virtual.author-orcid0000-0003-0135-4882
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cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid0000-0003-2220-2730
cris.virtualsource.author-orcid06272a0f-88ac-488a-98f3-354fd0fc93cc
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid71dccebf-e765-40b9-87bb-e98ab3b7299c
dc.abstract.enThe aim of this review is to present current knowledge regarding acute phase proteins (APPs) in selected wild mammal species. APPs are a group of proteins synthesized in the liver. Their main biological function is to restore homeostasis in response to infection, injury, and other pathologies. APPs are well-studied and used in routine diagnostics in domestic animals and humans, whereas in wildlife species they are currently under intensive research. The most investigated APPs in non-domesticated animals include serum amyloid A (SAA), haptoglobin (Hp), C-reactive protein (CRP), fibrinogen (Fb), ceruloplasmin (Cp), and albumins (Ab). Changes in their concentrations have been described in cases of injuries, bacterial and viral infections, parasite infestations, and stress situations. It is important to note that the concentration of APPs is strongly affected by species, genotype, age, and environmental conditions. As the knowledge regarding APPs in wildlife develops, they may possibly be used in the future as diagnostic or prognostic tools, which is of special importance for threatened wildlife species.
dc.affiliationWydział Medycyny Weterynaryjnej i Nauk o Zwierzętach
dc.affiliation.instituteKatedra Nauk Przedklinicznych i Chorób Zakaźnych
dc.contributor.authorLibera, Kacper
dc.contributor.authorSzopka, Wiktoria
dc.contributor.authorRatajczak, Agata M.
dc.contributor.authorPomorska-Mól, Małgorzata
dc.date.access2026-03-09
dc.date.accessioned2026-03-09T13:25:29Z
dc.date.available2026-03-09T13:25:29Z
dc.date.copyright2022-03-11
dc.date.issued2022
dc.description.abstract<jats:p>The aim of this review is to present current knowledge regarding acute phase proteins (APPs) in selected wild mammal species. APPs are a group of proteins synthesized in the liver. Their main biological function is to restore homeostasis in response to infection, injury, and other pathologies. APPs are well-studied and used in routine diagnostics in domestic animals and humans, whereas in wildlife species they are currently under intensive research. The most investigated APPs in non-domesticated animals include serum amyloid A (SAA), haptoglobin (Hp), C-reactive protein (CRP), fibrinogen (Fb), ceruloplasmin (Cp), and albumins (Ab). Changes in their concentrations have been described in cases of injuries, bacterial and viral infections, parasite infestations, and stress situations. It is important to note that the concentration of APPs is strongly affected by species, genotype, age, and environmental conditions. As the knowledge regarding APPs in wildlife develops, they may possibly be used in the future as diagnostic or prognostic tools, which is of special importance for threatened wildlife species.</jats:p>
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if0,4
dc.description.number6
dc.description.points70
dc.description.versionfinal_published
dc.description.volume78
dc.identifier.doi10.21521/mw.6662
dc.identifier.issn0025-8628
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/7753
dc.identifier.weblinkhttps://www.medycynawet.edu.pl/archives/summary/927-summary-2022/934-summary-062022/6662-summary-med-weter-78-06-6662-2022
dc.languageen
dc.relation.ispartofMedycyna Weterynaryjna
dc.relation.pages272-278
dc.rightsCC-BY-SA
dc.sciencecloudnosend
dc.share.typeOPEN_JOURNAL
dc.subject.enserum amyloid A
dc.subject.enhaptoglobin
dc.subject.enfibrinogen
dc.subject.enceruloplasmin
dc.subtypeReviewArticle
dc.titleAcute phase proteins in wildlife and their domesticated relatives
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue06
oaire.citation.volume78