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Szczepionka przeciwko afrykańskiemu pomorowi świń - gdzie jesteśmy i dokąd zmierzamy

cris.virtual.author-orcid0000-0003-2220-2730
cris.virtual.author-orcid0000-0002-4509-8852
cris.virtual.author-orcid0000-0002-1610-0589
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid71dccebf-e765-40b9-87bb-e98ab3b7299c
cris.virtualsource.author-orcid702c3b7e-b378-411f-bc9b-510fe73f43da
cris.virtualsource.author-orcidcfb82b96-7ef9-4b03-b4fb-1a3075fd805e
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.abstract.enAfrican swine fever (ASF), is a viral disease of pigs and wild boar that is usually deadly. There are neither vaccines nor cures. African swine fever has got a significant negative impact on the global pig industry. The disease control is based on ensuring biosecurity, early diagnosis and culling pig herds with ASFVinfected animals. However, in view of the ease with which ASFV spreads, its high resistance to environmental conditions and the many difficulties related to the introduction of effective specific immunoprophylaxis, this process is extremely difficult. Despite incountering problems such as lack of an animal model other than the natural host, lack of an effective continuous cell line for the isolation and propagation of ASFV, a risk of reversion to virulence, or inability to differentiate infected animals from vaccinated ones, scientists do not stop trying to design an effective vaccine. Recent approaches to ASF vaccine construction have focused on the development of modified live vaccines by targeted gene deletion from different isolates or of subunit vaccines. Here, we discuss current scientific advances and technological progress in this issue. The design of a safe and effective vaccine against ASFV seems to be achievable, nevertheless, a commercial vaccine is unlikely to appear within the next few years.
dc.affiliationWydział Medycyny Weterynaryjnej i Nauk o Zwierzętach
dc.affiliation.instituteKatedra Nauk Przedklinicznych i Chorób Zakaźnych
dc.contributor.authorPomorska-Mól, Małgorzata
dc.contributor.authorTurlewicz-Podbielska, Hanna
dc.contributor.authorAugustyniak, Agata
dc.contributor.authorKucińśka, Izabela
dc.date.access2026-01-12
dc.date.accessioned2026-01-13T06:52:13Z
dc.date.available2026-01-13T06:52:13Z
dc.date.copyright2022-06
dc.date.issued2022
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.number6
dc.description.points5
dc.description.versionfinal_published
dc.identifier.eissn1689-0299
dc.identifier.issn0137-6810
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/6757
dc.identifier.weblinkhttps://zycie-weterynaryjne.pl/rocznik-97-rok-2022/
dc.languagepl
dc.language.otheren
dc.relation.ispartofŻycie Weterynaryjne
dc.relation.pages378-384
dc.rightsOther
dc.sciencecloudnosend
dc.share.typeOTHER
dc.subject.envaccine
dc.subject.enAfrican swine fever
dc.subject.enimmunoprophylaxis
dc.titleSzczepionka przeciwko afrykańskiemu pomorowi świń - gdzie jesteśmy i dokąd zmierzamy
dc.title.alternativeVaccine against African swine fever - where are we and where are we going?
dc.typeJournalArticle
dspace.entity.typePublication