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Assessing species bias in amphibian research on endocrine disruptors: beyond Xenopus laevis

cris.virtual.author-orcid0000-0002-3341-0933
cris.virtual.author-orcid0000-0002-6828-0534
cris.virtual.author-orcid0000-0002-8358-0797
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid1f7c3a90-493f-47c8-a396-aab527605ee8
cris.virtualsource.author-orciddaf06652-dcef-4aa8-b66a-bdb14028e85d
cris.virtualsource.author-orcid362c6679-6484-44a9-a5b6-eaf80f4cee38
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.abstract.enDue to their high sensitivity to hormonal agents, in recent years, amphibians have been proposed as bioindicators for the presence of endocrine-disrupting compounds (EDCs) in the environment. EDCs are a chemically diverse group of compounds, mainly of anthropogenic origin, that can interfere with hormone receptors. The escalating global environmental pollution with endocrine-disrupting compounds (EDCs) poses a significant threat to wildlife and human health. Amphibians are at high risk of exposure to EDCs in the environment, as they produce eggs without a protective shell, possess highly permeable skin, and most of them undergo an aquatic life phase, where they are chronically exposed to EDCs in the water. This exposure raises concerns about the contribution of EDCs to the dramatic decline of amphibian populations and underscores the necessity of environmental-relevant studies in this area. Despite the critical need, amphibians have attracted relatively little research focus in this regard. Although above 200 experimental studies on the topic of EDCs and sex, reproduction, and related traits in amphibians have been conducted, a significant portion of them rely on model species from the Xenopus genus, which do not fully represent the diverse group of amphibians. Additionally, these studies often use strict laboratory conditions that fail to mimic natural exposure scenarios. Our extensive review highlights the research gaps and emphasizes the importance of incorporating a broader range of amphibian species to understand the true impact of EDCs. We advocate for more studies in environmentally relevant settings and the use of native species to enhance the ecological validity of findings.
dc.affiliationWydział Medycyny Weterynaryjnej i Nauk o Zwierzętach
dc.affiliation.instituteKatedra Zoologii
dc.affiliation.instituteKatedra Fizjologii, Biochemii i Biostruktury Zwierząt
dc.contributor.authorFrątczak, Martyna
dc.contributor.authorKaczmarski, Mikołaj
dc.contributor.authorSzkudelska, Katarzyna
dc.contributor.authorTryjanowski, Piotr
dc.date.access2025-06-17
dc.date.accessioned2025-06-17T12:15:59Z
dc.date.available2025-06-17T12:15:59Z
dc.date.copyright2025-05-14
dc.date.issued2025
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financeother
dc.description.financecost17822,70
dc.description.if3,3
dc.description.points100
dc.description.versionfinal_published
dc.description.volume13
dc.identifier.doi10.3389/fenvs.2025.1556788
dc.identifier.eissn2296-665X
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/2862
dc.identifier.weblinkhttps://www.frontiersin.org/journals/environmental-science/articles/10.3389/fenvs.2025.1556788/full
dc.languageen
dc.pbn.affiliationbiological sciences
dc.relation.ispartofFrontiers in Environmental Science
dc.relation.pagesart. 1556788
dc.relation.projectPRELUDIUM UMO 2023/49/N/NZ8/01103
dc.rightsCC-BY
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.enEDC
dc.subject.enenvironmental pollution
dc.subject.enmodel species
dc.subject.enecotoxicology
dc.subject.enone health
dc.subtypeReviewArticle
dc.titleAssessing species bias in amphibian research on endocrine disruptors: beyond Xenopus laevis
dc.typeJournalArticle
dspace.entity.typePublication
project.funder.nameprojekt PRELUDIUM UMO 2023/49/N/NZ8/01103
project.funder.namePolish Minister of Science and Higher Education as part of the Strategy of the Poznan University of Life Sciences for 2024-2026