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“CLINICAL-BFR”: An exploratory blood flow restriction protocol focusing on clinical application

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cris.virtual.author-orcid0000-0002-9030-1805
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dc.abstract.enPurpose Traditional blood flow restriction resistance training (BFR-Trad) is a cost-effective and time-efficient exercise modality that offers significant skeletal muscle benefits, including strength and mass gains. Despite employing low loads, BFR-Trad may not be well tolerated by all populations due to its high intensity, pain-associated muscle discomfort, low affectivity, and cardiovascular responses. Consequently, reducing BFR intensity may be an interesting approach to making traditional BFR more clinically applicable. This was approached through the proposal of the present Clinical BFR. Methods Twenty-two healthy, untrained subjects (both female and male) aged between 18 and 30 years participated. Subjects completed three sessions of unilateral knee extension exercises randomly assigned to the BFR-Trad, BFR-Clinical_c (cadenced), and BFR-Clinical_a (-autoregulated) exercise protocols. Results The BFR-Trad condition induced greater increases in perceived exertion, discomfort, delayed onset muscle soreness (DOMS), and lactate levels compared to the BFR-Clinical conditions (p ​< ​0.05). Muscle concentric velocity showed greater increases in the BFR-Clinical_a condition (p ​< ​0.001), along with higher affectivity ratings for the exercise compared to the BFR-Clinical_c and BFR-Trad conditions (p ​< ​0.05). Conclusion Compared to traditional BFR, clinical BFR was scored as less intense, reduced pain-associated discomfort, decreased DOMS, increased affectivity, diminished systolic blood pressure responses, decreased fatigue and muscle activation, and promoted similar glycemic responses. Altogether, our results support the potential use of clinical BFR in clinical settings.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Żywienia Człowieka i Dietetyki
dc.contributor.authorRossi, Fabricio Eduardo
dc.contributor.authorde Araújo Pessôa, Kassiana
dc.contributor.authorXia, Zhi
dc.contributor.authorLauver, Jakob
dc.contributor.authorNewmire, Daniel
dc.contributor.authorCholewa, Jason Michael
dc.contributor.authorMachek, Steven
dc.contributor.authorAlves de Siqueira Filho, Mario
dc.contributor.authorLira, Fabio Santos
dc.contributor.authorLancha-Jr, Antonio Herbert
dc.contributor.authorZawieja, Emilia
dc.contributor.authorZanchi, Nelo Eidy
dc.date.access2025-08-19
dc.date.accessioned2025-08-19T12:30:13Z
dc.date.available2025-08-19T12:30:13Z
dc.date.copyright2025-06-14
dc.date.issued2025
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.versionfinal_published
dc.identifier.doi10.1016/j.smhs.2025.06.005
dc.identifier.issn2666-3376
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/4294
dc.identifier.weblinkhttps://www.sciencedirect.com/science/article/pii/S266633762500071X
dc.languageen
dc.relation.ispartofSports Medicine and Health Science
dc.rightsCC-BY-NC-ND
dc.sciencecloudnosend
dc.share.typeOPEN_JOURNAL
dc.subject.enresistance training
dc.subject.enblood flow restriction
dc.subject.enmuscle power
dc.subject.endiscomfort
dc.subject.enmuscle fatigue
dc.subtypeArticleEarlyAccess
dc.title“CLINICAL-BFR”: An exploratory blood flow restriction protocol focusing on clinical application
dc.typeJournalArticle
dspace.entity.typePublication