Dependence in Activities of Daily Living as a Predictor of In-Hospital Mortality During COVID-19 in Older Individuals

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dc.abstract.enActivities of Daily Living (ADL) are fundamental tasks for individuals to manage their basic needs. Our study aims to examine ADL at admission (adADL) and the Pre-COVID-19 to Admission ADL Difference (ADL-change) as potential predictors of in-hospital mortality. This is a retrospective analysis of clinical data (including the Katz index for ADL) from 141 older patients aged at least 65 years hospitalized in a COVID-19-dedicated unit (not requiring ICU) from September 2021 until January 2022 in Poznań, Poland. Thirty patients (21.3% of all) died during hospitalization. Non-survivors were older than survivors, exhibited lower oxygen saturation, more severe inflammation, higher D-dimer concentrations, and were more commonly prescribed antibiotics. The AUC for in-hospital mortality was for adADL: 0.7417 (95% CI: 0.6478–0.8357; p < 0.0001) and for ADL-change: 0.6869 (95% CI: 0.579–0.7928; p = 0.0018). The corresponding cut-offs were 0 for adADL and 3 for ADL-change. Cox proportional hazard models yielded hazard ratios of 3.57 (95% CI 1.57–8.10; p = 0.0024) for adADL and 3.78 (95% CI 1.49–9.54; p = 0.005) for ADL-change. ADL assessment offers valuable insights into in-hospital mortality among older COVID-19 patients. Monitoring ADL in these patients indicates high-risk individuals for in-hospital death. Integrating ADL into routine clinical practice might enhance care for older patients.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Żywienia Człowieka i Dietetyki
dc.contributor.authorIlkowski, Jan
dc.contributor.authorWieczorowska-Tobis, Katarzyna
dc.contributor.authorGuzik, Przemyslaw
dc.date.access2026-02-04
dc.date.accessioned2026-02-05T08:44:04Z
dc.date.available2026-02-05T08:44:04Z
dc.date.copyright2025-02-11
dc.date.issued2025
dc.description.abstract<jats:p>Activities of Daily Living (ADL) are fundamental tasks for individuals to manage their basic needs. Our study aims to examine ADL at admission (adADL) and the Pre-COVID-19 to Admission ADL Difference (ADL-change) as potential predictors of in-hospital mortality. This is a retrospective analysis of clinical data (including the Katz index for ADL) from 141 older patients aged at least 65 years hospitalized in a COVID-19-dedicated unit (not requiring ICU) from September 2021 until January 2022 in Poznań, Poland. Thirty patients (21.3% of all) died during hospitalization. Non-survivors were older than survivors, exhibited lower oxygen saturation, more severe inflammation, higher D-dimer concentrations, and were more commonly prescribed antibiotics. The AUC for in-hospital mortality was for adADL: 0.7417 (95% CI: 0.6478–0.8357; p &lt; 0.0001) and for ADL-change: 0.6869 (95% CI: 0.579–0.7928; p = 0.0018). The corresponding cut-offs were 0 for adADL and 3 for ADL-change. Cox proportional hazard models yielded hazard ratios of 3.57 (95% CI 1.57–8.10; p = 0.0024) for adADL and 3.78 (95% CI 1.49–9.54; p = 0.005) for ADL-change. ADL assessment offers valuable insights into in-hospital mortality among older COVID-19 patients. Monitoring ADL in these patients indicates high-risk individuals for in-hospital death. Integrating ADL into routine clinical practice might enhance care for older patients.</jats:p>
dc.description.accesstimeat_publication
dc.description.bibliographybibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if3,4
dc.description.number2
dc.description.points70
dc.description.versionfinal_published
dc.description.volume15
dc.identifier.doi10.3390/life15020271
dc.identifier.issn2075-1729
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/7161
dc.identifier.weblinkhttps://www.mdpi.com/2075-1729/15/2/271
dc.languageen
dc.relation.ispartofLife (Basel).
dc.relation.pagesart. 271
dc.rightsCC-BY
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.enactivities of daily living
dc.subject.enolder individuals
dc.subject.enin-hospital mortality
dc.subject.enCOVID-19
dc.titleDependence in Activities of Daily Living as a Predictor of In-Hospital Mortality During COVID-19 in Older Individuals
dc.title.volumeSpecial Issue Human Health Before, During, and After COVID-19
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue2
oaire.citation.volume15