Dependence in Activities of Daily Living as a Predictor of In-Hospital Mortality During COVID-19 in Older Individuals
| cris.virtual.author-orcid | #PLACEHOLDER_PARENT_METADATA_VALUE# | |
| cris.virtual.author-orcid | 0000-0003-4017-3013 | |
| cris.virtual.author-orcid | #PLACEHOLDER_PARENT_METADATA_VALUE# | |
| cris.virtualsource.author-orcid | #PLACEHOLDER_PARENT_METADATA_VALUE# | |
| cris.virtualsource.author-orcid | ddf914d5-8304-4221-a2f3-9b87de77dd45 | |
| cris.virtualsource.author-orcid | #PLACEHOLDER_PARENT_METADATA_VALUE# | |
| dc.abstract.en | Activities of Daily Living (ADL) are fundamental tasks for individuals to manage their basic needs. Our study aims to examine ADL at admission (adADL) and the Pre-COVID-19 to Admission ADL Difference (ADL-change) as potential predictors of in-hospital mortality. This is a retrospective analysis of clinical data (including the Katz index for ADL) from 141 older patients aged at least 65 years hospitalized in a COVID-19-dedicated unit (not requiring ICU) from September 2021 until January 2022 in Poznań, Poland. Thirty patients (21.3% of all) died during hospitalization. Non-survivors were older than survivors, exhibited lower oxygen saturation, more severe inflammation, higher D-dimer concentrations, and were more commonly prescribed antibiotics. The AUC for in-hospital mortality was for adADL: 0.7417 (95% CI: 0.6478–0.8357; p < 0.0001) and for ADL-change: 0.6869 (95% CI: 0.579–0.7928; p = 0.0018). The corresponding cut-offs were 0 for adADL and 3 for ADL-change. Cox proportional hazard models yielded hazard ratios of 3.57 (95% CI 1.57–8.10; p = 0.0024) for adADL and 3.78 (95% CI 1.49–9.54; p = 0.005) for ADL-change. ADL assessment offers valuable insights into in-hospital mortality among older COVID-19 patients. Monitoring ADL in these patients indicates high-risk individuals for in-hospital death. Integrating ADL into routine clinical practice might enhance care for older patients. | |
| dc.affiliation | Wydział Nauk o Żywności i Żywieniu | |
| dc.affiliation.institute | Katedra Żywienia Człowieka i Dietetyki | |
| dc.contributor.author | Ilkowski, Jan | |
| dc.contributor.author | Wieczorowska-Tobis, Katarzyna | |
| dc.contributor.author | Guzik, Przemyslaw | |
| dc.date.access | 2026-02-04 | |
| dc.date.accessioned | 2026-02-05T08:44:04Z | |
| dc.date.available | 2026-02-05T08:44:04Z | |
| dc.date.copyright | 2025-02-11 | |
| dc.date.issued | 2025 | |
| dc.description.abstract | <jats:p>Activities of Daily Living (ADL) are fundamental tasks for individuals to manage their basic needs. Our study aims to examine ADL at admission (adADL) and the Pre-COVID-19 to Admission ADL Difference (ADL-change) as potential predictors of in-hospital mortality. This is a retrospective analysis of clinical data (including the Katz index for ADL) from 141 older patients aged at least 65 years hospitalized in a COVID-19-dedicated unit (not requiring ICU) from September 2021 until January 2022 in Poznań, Poland. Thirty patients (21.3% of all) died during hospitalization. Non-survivors were older than survivors, exhibited lower oxygen saturation, more severe inflammation, higher D-dimer concentrations, and were more commonly prescribed antibiotics. The AUC for in-hospital mortality was for adADL: 0.7417 (95% CI: 0.6478–0.8357; p < 0.0001) and for ADL-change: 0.6869 (95% CI: 0.579–0.7928; p = 0.0018). The corresponding cut-offs were 0 for adADL and 3 for ADL-change. Cox proportional hazard models yielded hazard ratios of 3.57 (95% CI 1.57–8.10; p = 0.0024) for adADL and 3.78 (95% CI 1.49–9.54; p = 0.005) for ADL-change. ADL assessment offers valuable insights into in-hospital mortality among older COVID-19 patients. Monitoring ADL in these patients indicates high-risk individuals for in-hospital death. Integrating ADL into routine clinical practice might enhance care for older patients.</jats:p> | |
| dc.description.accesstime | at_publication | |
| dc.description.bibliography | bibliogr. | |
| dc.description.finance | publication_nocost | |
| dc.description.financecost | 0,00 | |
| dc.description.if | 3,4 | |
| dc.description.number | 2 | |
| dc.description.points | 70 | |
| dc.description.version | final_published | |
| dc.description.volume | 15 | |
| dc.identifier.doi | 10.3390/life15020271 | |
| dc.identifier.issn | 2075-1729 | |
| dc.identifier.uri | https://sciencerep.up.poznan.pl/handle/item/7161 | |
| dc.identifier.weblink | https://www.mdpi.com/2075-1729/15/2/271 | |
| dc.language | en | |
| dc.relation.ispartof | Life (Basel). | |
| dc.relation.pages | art. 271 | |
| dc.rights | CC-BY | |
| dc.sciencecloud | send | |
| dc.share.type | OPEN_JOURNAL | |
| dc.subject.en | activities of daily living | |
| dc.subject.en | older individuals | |
| dc.subject.en | in-hospital mortality | |
| dc.subject.en | COVID-19 | |
| dc.title | Dependence in Activities of Daily Living as a Predictor of In-Hospital Mortality During COVID-19 in Older Individuals | |
| dc.title.volume | Special Issue Human Health Before, During, and After COVID-19 | |
| dc.type | JournalArticle | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 2 | |
| oaire.citation.volume | 15 |