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Assessment of clinical outcome after sudden alteration of home parenteral nutrition program from customised to commercially premixed admixtures. Experience with short bowel syndrome treatment

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cris.virtual.author-orcid0000-0003-2793-7074
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dc.abstract.enBackground & aims Disruptions in the home parenteral nutrition (HPN) process may lead to failure to achieve the intended treatment purposes. This study aimed to evaluate the mid-term clinical outcome in a group of patients with short bowel syndrome (SBS) after a sudden change in the type of home parenteral nutrition programs from customized to commercially premixed admixtures. Methods The study conducted in 2020 identified 51 patients with SBS: 27 (53%) women and 24 (47%) men. The SBS were classified as SBS with end jejunostomy 23 (45%) patients, with jejuno-colon anastomosis 23 (45%) patients, with jejuno-ileo anastomosis and total colon in continuity 5 (10%) patients. The following therapeutic program-related data were analysed: changes in nutritional status, body mass index (BMI), Controlling Nutritional Status (CONUT) score, and biochemical assessment. For statistical analysis, the Wilcoxon rank-sum and signed-rank paired tests with continuity corrections were used to compare the results. A p-value of <0.001 was considered statistically significant. Results There was no statistically significant difference between the analysed groups in total energy, amino acid concentrations, and intravenous volume supplementation. BMI and CONUT assessments of nutritional status and selected biochemical parameters were stable during the study period. Conclusions The study demonstrated that a sudden change in the HPN therapy program from parenteral admixtures, tailored to meet individual patients’ needs, to commercially premixed admixtures had no significant impact on the mid-term clinical condition of patients with SBS.
dc.affiliationWydział Rolnictwa, Ogrodnictwa i Bioinżynierii
dc.affiliation.instituteKatedra Metod Matematycznych i Statystycznych
dc.contributor.authorMatysiak, Konrad
dc.contributor.authorSzewczuk, Magdalena
dc.contributor.authorNapierała, Agnieszka
dc.contributor.authorNowak, Krzrzysztof
dc.contributor.authorOlijarczyk, Rafał
dc.contributor.authorSiatkowski, Idzi
dc.date.accessioned2025-07-22T09:35:30Z
dc.date.available2025-07-22T09:35:30Z
dc.date.issued2024
dc.description.bibliographybibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if2,6
dc.description.numberApril 2024
dc.description.points40
dc.description.volume60
dc.identifier.doi10.1016/j.clnesp.2024.02.020
dc.identifier.issn2405-4577
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/3920
dc.languageen
dc.relation.ispartofClinical Nutrition ESPEN
dc.relation.pages298-302
dc.rightsClosedAccess
dc.sciencecloudsend
dc.subject.enhome parenteral nutrition
dc.subject.enschort bowel syndrome
dc.subject.enchronic intestinale failure
dc.titleAssessment of clinical outcome after sudden alteration of home parenteral nutrition program from customised to commercially premixed admixtures. Experience with short bowel syndrome treatment
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.volume60