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The in vitro effects of probiotic bacteria on genital pathogens of female dogs

cris.lastimport.scopus2025-10-23T06:58:38Z
cris.virtual.author-orcid0000-0002-6576-8972
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dc.abstract.enBackground An important aspect in the microbiology of the reproductive system of small animals is the potential occurrence of probiotic bacteria, such as lactic acid bacteria (LAB) of the genus Lactobacillus. The presence of these microorganisms is significant due to their strong antibacterial and antifungal properties. This study aimed to select probiotic strains from the oral cavity and vagina that have outstanding antibacterial properties against typical genital pathogens of the female dog reproductive tract. Results The antagonistic activity of ten LAB strains was tested against seven etiological agents isolated from the genital tract of female dogs with signs of inflammation. LAB strains with the greatest ability to inhibit the growth of indicator bacteria were Lactobacillus plantarum and L. acidophilus, while L. fermentum and L. brevis strains inhibited growth the least. Almost all strains showed a complete lack of adherence to Caco-2 epithelial cells. Conclusions All tested LAB isolates inhibited the in vitro growth of either Gram-positive or Gram-negative pathogens, suggesting that potential probiotic strains could contribute to the balance of the normal vaginal microbiota. Furthermore, they could be considered for use as prophylactic agents or as an alternative to antibiotic therapy for infections in dogs.
dc.affiliationWydział Medycyny Weterynaryjnej i Nauk o Zwierzętach
dc.affiliation.instituteKatedra Genetyki i Podstaw Hodowli Zwierząt​​
dc.contributor.authorGolińska, Edyta
dc.contributor.authorSowińska, Natalia
dc.contributor.authorSzydło, Marlena
dc.contributor.authorWitka, Natalia
dc.contributor.authorLenarczyk, Joanna
dc.contributor.authorZbigniew, Arent
dc.contributor.authorStrus, Magdalena
dc.date.access2025-06-09
dc.date.accessioned2025-09-18T07:06:53Z
dc.date.available2025-09-18T07:06:53Z
dc.date.copyright2023-07-08
dc.date.issued2023
dc.description.abstract<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>An important aspect in the microbiology of the reproductive system of small animals is the potential occurrence of probiotic bacteria, such as lactic acid bacteria (LAB) of the genus <jats:italic>Lactobacillus</jats:italic>. The presence of these microorganisms is significant due to their strong antibacterial and antifungal properties. This study aimed to select probiotic strains from the oral cavity and vagina that have outstanding antibacterial properties against typical genital pathogens of the female dog reproductive tract.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The antagonistic activity of ten LAB strains was tested against seven etiological agents isolated from the genital tract of female dogs with signs of inflammation. LAB strains with the greatest ability to inhibit the growth of indicator bacteria were <jats:italic>Lactobacillus plantarum</jats:italic> and <jats:italic>L. acidophilus</jats:italic>, while <jats:italic>L. fermentum</jats:italic> and <jats:italic>L. brevis</jats:italic> strains inhibited growth the least. Almost all strains showed a complete lack of adherence to Caco-2 epithelial cells.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>All tested LAB isolates inhibited the in vitro growth of either Gram-positive or Gram-negative pathogens, suggesting that potential probiotic strains could contribute to the balance of the normal vaginal microbiota. Furthermore, they could be considered for use as prophylactic agents or as an alternative to antibiotic therapy for infections in dogs.</jats:p> </jats:sec>
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if2,3
dc.description.points140
dc.description.versionfinal_published
dc.description.volume19
dc.identifier.doi10.1186/s12917-023-03635-y
dc.identifier.issn1746-6148
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/4901
dc.identifier.weblinkhttps://bmcvetres.biomedcentral.com/articles/10.1186/s12917-023-03635-y
dc.languageen
dc.relation.ispartofBMC Veterinary Research
dc.relation.pagesart. 82
dc.rightsCC-BY
dc.sciencecloudnosend
dc.share.typeOPEN_JOURNAL
dc.subject.enantibacterial activity
dc.subject.envaginal microflora
dc.subject.endog
dc.subject.enLactobacillus
dc.subject.enprob
dc.titleThe in vitro effects of probiotic bacteria on genital pathogens of female dogs
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.volume19