Simple item page
 

Impact of bisphenol A and ethinyloestradiol on sex, body condition and digit ratio of the marsh frog Pelophylax ridibundus in the mesocosm exposure system

cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid0000-0002-6828-0534
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid0000-0002-3341-0933
cris.virtual.author-orcid0000-0002-9305-2306
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid0000-0002-8358-0797
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orciddaf06652-dcef-4aa8-b66a-bdb14028e85d
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid1f7c3a90-493f-47c8-a396-aab527605ee8
cris.virtualsource.author-orcid7fdc089b-49be-41f2-b6f6-6d640ef0f9d5
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid362c6679-6484-44a9-a5b6-eaf80f4cee38
dc.abstract.enThis study examined the impact of two environmentally widespread endocrine-disrupting compounds (EDCs), bisphenol A (BPA) and 17α-ethinylestradiol (EE2), on the marsh frog Pelophylax ridibundus. The analysis focused on somatic condition, gonadal differentiation, and the second-to-fourth digit ratio (DR, 2D:4D), tested as a potential non-invasive biomarker of endocrine disruption. Tadpoles were reared in outdoor mesocosms and exposed weekly to three environmentally-relevant concentrations of BPA (BPA7 - 10⁻⁷, BPA8 - 10⁻⁸, BPA9 - 10⁻⁹ M) and one concentration of EE2 (10⁻⁹ M), acting as a positive control. The exposition was conducted in a static-renewal system. While neither treatment nor sex influenced snout–vent length (SVL) or body weight, Scale Mass Index (SMI) was significantly reduced in the highest concentration BPA group (–0.139 ± 0.036) and in EE2 (–0.173 ± 0.036), indicating impaired somatic condition. EE2 caused a strikingly female-biased sex ratio (≈9:1 F:M), increasing the odds of being female by 5.2-fold, whereas BPA did not affect sex ratios. Histological analyses revealed two intersex and one mixed-sex individuals in the EE2 group. In the number of BPA-exposed males, significant gonadal degeneration and rudimentary metamers were observed, with similar structures found in females, suggesting disturbed gonadal development. Although DR did not differ between sexes, both EE2 and BPA altered it in a size-dependent manner, with significant treatment × SVL interactions in hindlimbs (EE2, BPA7) and the left forelimb (EE2), where larger individuals exhibited lower ratios under exposure. These environmentally relevant findings demonstrate that BPA and EE2 profoundly disrupt somatic health, gonadal differentiation and sex-related traits in a non-model amphibian species, with clear implications for wildlife conservation.
dc.affiliationWydział Medycyny Weterynaryjnej i Nauk o Zwierzętach
dc.affiliation.instituteKatedra Zoologii
dc.affiliation.instituteKatedra Fizjologii, Biochemii i Biostruktury Zwierząt
dc.contributor.authorFrątczak, Martyna
dc.contributor.authorSzkudelska, Katarzyna
dc.contributor.authorGrobelna, Marta
dc.contributor.authorHermaniuk, Adam
dc.contributor.authorJankowiak, Łukasz
dc.contributor.authorKaczmarski, Mikołaj
dc.contributor.authorMyczko, Łukasz
dc.contributor.authorRozenblut-Kościsty, Beata
dc.contributor.authorTryjanowski, Piotr
dc.date.access2026-04-10
dc.date.accessioned2026-04-10T10:32:52Z
dc.date.available2026-04-10T10:32:52Z
dc.date.copyright2026-03-07
dc.date.issued2026
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if4,3
dc.description.numberMay 2026
dc.description.points140
dc.description.versionfinal_published
dc.description.volume294
dc.identifier.doi10.1016/j.aquatox.2026.107788
dc.identifier.eissn1879-1514
dc.identifier.issn0166-445X
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/8055
dc.identifier.weblinkhttps://www.sciencedirect.com/science/article/pii/S0166445X26000858
dc.languageen
dc.relation.ispartofAquatic Toxicology
dc.relation.pagesart. 107788
dc.rightsCC-BY
dc.sciencecloudnosend
dc.share.typeOTHER
dc.subject.enecotoxicology
dc.subject.enamphibians
dc.subject.enendocrine-disrupting compounds
dc.subject.enEDC
dc.subject.en2D:4D
dc.subject.enEuropean water frogs
dc.titleImpact of bisphenol A and ethinyloestradiol on sex, body condition and digit ratio of the marsh frog Pelophylax ridibundus in the mesocosm exposure system
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.volume294