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Torilis arvensis ethanolic extract: Phytochemical analysis, antifungal efficacy, and cytotoxicity properties

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dc.abstract.enThe aim of the current study is to assess the phytochemical contents, antifungal activity, and cytotoxicity characteristics of an ethanolic extract derived from the entire Torilis arvensis plant. High-performance liquid chromatography examination of the extract revealed that the primary phenolic components were benzoic, o-coumaric, and vanillic acids with concentrations of 259.1, 220.4, and 111.3 µg/g of extract, respectively. The highest flavonoids were catechol (117.9µg/g) and kaempferol (108.7µg/g). The extract is notable for its high concentration of long-chain saturated and unsaturated fatty acids, as well as its presence of 17 gas chromatography-mass spectrometry bioactive chemicals. Three soil-borne pathogenic fungi, Rhizoctonia solani, Fusarium solani,andFusarium oxysporum, were molecularly identified and assessed for the antifungal activity of the extract. The extract showed the highest growth inhibition against R. solani, F. oxysporum,andF. solani at 300 µg/mL, with inhibition rates of 88.9, 71.5, and 67.8%, respectively. T. arvensis treatments were generally non-toxic after proceeding with cytotoxicity assay on the onion root tip cells, with nochromosomal abnormalities detected even at the highest concentration (300 µg/mL). These findings highlight the potential of T. arvensis extract as a safe and effective antifungal agent with a rich phytochemical profile.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Technologii Żywności Pochodzenia Roślinnego
dc.contributor.authorKhalil, Abdallah
dc.contributor.authorAbdelwahab, Eman A.
dc.contributor.authorSharaf, Omaima A.
dc.contributor.authorAl-Askar, Abdulaziz A.
dc.contributor.authorKowalczewski, Przemysław Łukasz
dc.contributor.authorAbdelkhalek, Ahmed
dc.contributor.authorBehiry, Said
dc.date.access2024-12-09
dc.date.accessioned2025-01-08T11:44:15Z
dc.date.available2025-01-08T11:44:15Z
dc.date.copyright2024-11-29
dc.date.issued2024
dc.description.abstract<jats:title>Abstract</jats:title> <jats:p>The aim of the current study is to assess the phytochemical contents, antifungal activity, and cytotoxicity characteristics of an ethanolic extract derived from the entire <jats:italic>Torilis arvensis</jats:italic> plant. High-performance liquid chromatography examination of the extract revealed that the primary phenolic components were benzoic, <jats:italic>o</jats:italic>-coumaric, and vanillic acids with concentrations of 259.1, 220.4, and 111.3 µg/g of extract, respectively. The highest flavonoids were catechol (117.9 µg/g) and kaempferol (108.7 µg/g). The extract is notable for its high concentration of long-chain saturated and unsaturated fatty acids, as well as its presence of 17 gas chromatography-mass spectrometry bioactive chemicals. Three soil-borne pathogenic fungi, <jats:italic>Rhizoctonia solani</jats:italic>, <jats:italic>Fusarium solani</jats:italic>, and <jats:italic>Fusarium oxysporum,</jats:italic> were molecularly identified and assessed for the antifungal activity of the extract. The extract showed the highest growth inhibition against <jats:italic>R. solani</jats:italic>, <jats:italic>F. oxysporum</jats:italic>, and <jats:italic>F. solani</jats:italic> at 300 µg/mL, with inhibition rates of 88.9, 71.5, and 67.8%, respectively. <jats:italic>T. arvensis</jats:italic> treatments were generally non-toxic after proceeding with cytotoxicity assay on the onion root tip cells, with no chromosomal abnormalities detected even at the highest concentration (300 µg/mL). These findings highlight the potential of <jats:italic>T. arvensis</jats:italic> extract as a safe and effective antifungal agent with a rich phytochemical profile.</jats:p>
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if2,1
dc.description.number1
dc.description.points70
dc.description.versionfinal_published
dc.description.volume22
dc.identifier.doi10.1515/chem-2024-0113
dc.identifier.issn2391-5420
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/2296
dc.identifier.weblinkhttps://www.degruyter.com/document/doi/10.1515/chem-2024-0113/html
dc.languageen
dc.relation.ispartofOpen Chemistry
dc.relation.pagesart. 20240113
dc.rightsCC-BY
dc.sciencecloudsend
dc.subject.enTorilis arvensis
dc.subject.ensecondary metabolites
dc.subject.enHPLC
dc.subject.enGC-MS
dc.subject.ensoil-borne fungi
dc.subject.encytotoxicity
dc.titleTorilis arvensis ethanolic extract: Phytochemical analysis, antifungal efficacy, and cytotoxicity properties
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.volume22