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Defeat undefeatable: Ionic liquids as novel antimicrobial agents

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cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
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cris.virtual.author-orcid0000-0003-3455-3044
cris.virtual.author-orcid0000-0003-3145-9407
cris.virtualsource.author-orcid8da63665-4835-4e83-a6d3-28544e67b2b4
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cris.virtualsource.author-orcid789ea30a-f0af-454d-b257-827c734e8291
cris.virtualsource.author-orcid94301770-9c63-42ac-aa65-6e7718de55c1
dc.abstract.enEmerging antimicrobial resistance and spread of drug-resistant pathogens is currently-one of the biggest threats posed to global health. Due to that, search of new antimicrobials replacing now used antibiotics has been given a very high priority. Ionic liquids; low-melting salts, thanks to their unique tunable nature and biological activity are considered as a group of candidate compounds to become antimicrobials of the future. This Review presents data collected on the effects of ionic liquids on pathogenic and non-pathogenic bacteria and viruses, focusing on the: (i) interactions between ionic liquids and key cell components including cell membranes, cell wall, proteins and nucleic acids; (ii) oxidative stress and metabolic dysregulation induced by ionic liquids; (iii) interactions of ionic liquids with bacterial biofilms; (iv) potential drawbacks related to the use of ionic liquids as antimicrobials.
dc.affiliationWydział Rolnictwa, Ogrodnictwa i Biotechnologii
dc.affiliation.instituteKatedra Biochemii i Biotechnologii
dc.contributor.authorMichalski, Jakub
dc.contributor.authorOdrzygóźdź, Cezary
dc.contributor.authorMester, Patrick
dc.contributor.authorNarożna, Dorota
dc.contributor.authorCłapa, Tomasz
dc.date.accessioned2025-09-04T11:59:58Z
dc.date.available2025-09-04T11:59:58Z
dc.date.issued2023
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if5,3
dc.description.number1 January 2023
dc.description.points100
dc.description.volume369
dc.identifier.doi10.1016/j.molliq.2022.120782
dc.identifier.eissn1873-3166
dc.identifier.issn0167-7322
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/4641
dc.languageen
dc.relation.ispartofJournal of Molecular Liquids
dc.relation.pagesart. 120782
dc.rightsClosedAccess
dc.sciencecloudsend
dc.subject.enionic liquids
dc.subject.enantimicrobial agents
dc.subject.enpathogens
dc.subject.enviruses
dc.titleDefeat undefeatable: Ionic liquids as novel antimicrobial agents
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.volume369