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Using Association Mapping to Identify Candidate Genes Associated with Infection Diseases Resistance

cris.virtual.author-orcid0000-0002-0102-0084
cris.virtualsource.author-orcid51a5a68b-106b-4e9d-bd9b-79d15d3ec0c1
dc.abstract.enInfectious diseases are responsible for a significant proportion of deaths in the world population. They are a major determinant of natural selection. Differential susceptibility to pathogens occurs among people from the same ethnic groups and belonging to different populations. The explanation for this phenomenon should be sought in the human genome. Ongoing research using commonly used genetic testing methods has made it possible to identify changes in certain genes that modulate an organism's susceptibility to a particular disease and the rate at which it develops. However, it is important to identify genes that determine resistance to infectious diseases. Genome-Wide Association Studies (GWAS) are a useful tool for identifying candidate genes, especially when combined with Quantitative Trait Loci (QTL) mapping to validate loci for observed traits.
dc.affiliationWydział Rolnictwa, Ogrodnictwa i Biotechnologii
dc.affiliation.instituteKatedra Metod Matematycznych i Statystycznych
dc.contributor.authorBocianowski, Jan
dc.date.access2024-09-17
dc.date.accessioned2024-10-23T09:07:11Z
dc.date.available2024-10-23T09:07:11Z
dc.date.copyright2024-06-12
dc.date.issued2024
dc.description.bibliographybibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.number4
dc.description.points5
dc.description.versionfinal_published
dc.description.volume12
dc.identifier.doi10.4172/2332-0877.1000594
dc.identifier.issn2332-0877
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/1915
dc.identifier.weblinkhttps://www.omicsonline.org/open-access/using-association-mapping-to-identify-candidate-genes-associated-with-infection-diseases-resistance-2332-0877-1000594-131176.html
dc.languageen
dc.relation.ispartofJournal of Infectious Diseases & Therapy
dc.relation.pagesart. 596
dc.rightsCC-BY
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.enGWAS analysis
dc.subject.enassociation mapping
dc.subject.eninfection diseases
dc.subject.enresistance
dc.titleUsing Association Mapping to Identify Candidate Genes Associated with Infection Diseases Resistance
dc.typeJournalArticle
dspace.entity.typePublication