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Concentrations of selected immunological parameters in the serum and processing fluid of suckling piglets and the serum and colostrum of their mothers

cris.virtual.author-orcid0000-0002-1610-0589
cris.virtual.author-orcid0000-0003-2220-2730
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcidcfb82b96-7ef9-4b03-b4fb-1a3075fd805e
cris.virtualsource.author-orcid71dccebf-e765-40b9-87bb-e98ab3b7299c
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.abstract.enBlood sampling from neonatal piglets is related to multiple disadvantages. Therefore, a new, alternative matrix is required to assess piglets’ early immune status efficiently. The present study aimed to assess the usefulness of processing fluid for determining selected piglets’ immune parameters. 264 pigs − 31 sows, 146 male piglets, and 87 female piglets from commercial indoor farrow-to-finish pig herd were included in this study. 264 serum, 31 colostrum, and 146 processing fluid samples were collected. Serum was collected from all animals, colostrum was collected from sows, and processing fluid was collected from male piglets only. Using commercial ELISA tests, the concentration of various immunoglobulins, cytokines, and acute phase proteins was assessed in each matrix. Statistical analyses were employed to determine differences in the concentration of measured indices between piglets’ serum and processing fluid and correlations in the concentration of tested indices between particular sets of matrices.
dc.affiliationWydział Medycyny Weterynaryjnej i Nauk o Zwierzętach
dc.affiliation.instituteKatedra Nauk Przedklinicznych i Chorób Zakaźnych
dc.affiliation.instituteKatedra Chorób Wewnętrznych i Diagnostyki
dc.article.number170
dc.contributor.authorAugustyniak, Agata
dc.contributor.authorCzyżewska-Dors, Ewelina
dc.contributor.authorPomorska-Mól, Małgorzata
dc.date.access2024
dc.date.accessioned2024-07-02T10:21:24Z
dc.date.available2024-07-02T10:21:24Z
dc.date.copyright2024-05-03
dc.date.issued2024
dc.description.abstract<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Blood sampling from neonatal piglets is related to multiple disadvantages. Therefore, a new, alternative matrix is required to assess piglets’ early immune status efficiently. The present study aimed to assess the usefulness of processing fluid for determining selected piglets’ immune parameters. 264 pigs − 31 sows, 146 male piglets, and 87 female piglets from commercial indoor farrow-to-finish pig herd were included in this study. 264 serum, 31 colostrum, and 146 processing fluid samples were collected. Serum was collected from all animals, colostrum was collected from sows, and processing fluid was collected from male piglets only. Using commercial ELISA tests, the concentration of various immunoglobulins, cytokines, and acute phase proteins was assessed in each matrix. Statistical analyses were employed to determine differences in the concentration of measured indices between piglets’ serum and processing fluid and correlations in the concentration of tested indices between particular sets of matrices.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Statistical analyses did not reveal significant differences in the IgG, IgA, IL-1β, IL-4, IL-6, and IFN-γ concentration between piglets’ serum and processing fluid (<jats:italic>p</jats:italic> &gt; 0.05). A positive correlation (<jats:italic>p</jats:italic> &lt; 0.05) regarding the concentration of some indices between processing fluid and samples collected from sows was also observed.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Processing fluid can be considered a promising alternative to blood for assessing some immunological indices in piglets, such as IgG, IgA, IL-1β, IL-4, IL-6, and IFN-γ, and, possibly, in the indirect assessment of some indices in lactating sows, including IgA, IL-1β, IL-4, IL-6, IL-8, IFN-γ, or Pig-MAP.</jats:p> </jats:sec>
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if2,3
dc.description.points140
dc.description.versionfinal_published
dc.description.volume20
dc.identifier.doi10.1186/s12917-024-04024-9
dc.identifier.issn1746-6148
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/1567
dc.identifier.weblinkhttps://bmcvetres.biomedcentral.com/articles/10.1186/s12917-024-04024-9
dc.languageen
dc.pbn.affiliationveterinary science
dc.relation.ispartofBMC Veterinary Research
dc.rightsCC-BY
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.enpigs
dc.subject.enneonate
dc.subject.enimmunoglobulins
dc.subject.encytokines
dc.subject.enmatrices
dc.subject.enprocessing fluid
dc.subject.enacute phase proteins
dc.titleConcentrations of selected immunological parameters in the serum and processing fluid of suckling piglets and the serum and colostrum of their mothers
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.volume20
project.funder.nameinne