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Studies on the formulation and functionality of an innovative line of topical products for atopic skin

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cris.virtual.author-orcid0000-0002-4665-1576
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cris.virtualsource.author-orcide5614862-91e0-4afe-b8e2-932fc4a17c0c
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dc.abstract.enDermocosmetics are products intended for sensitive and problematic skin. They are a good solution for additional care of skin affected by conditions such as atopic dermatitis, acne, psoriasis, or for couperose skin. The compounds of particular importance in the care of atopic skin include ceramides, ectoine, hyaluronic acid, vitamins A and E, as well as natural vegetable oils. The aim of this work was to develop a qualitative and quantitative approach and to investigate the characteristics of formulations such as a face cream, topical cream, body lotion, and cleansing foam dedicated to patients with atopic dermatitis. The finished cosmetic formulation was evaluated by performing formulation stability tests at different times and temperatures, together with packaging compatibility and organoleptic evaluation. Preservative tests were carried out to determine the efficacy of the preservative. In addition, dermatological and instrumental tests were done to verify the product properties. The newly developed cosmetic formulations showed good physical and chemical characteristics, typical of this type of product. They were also structurally and microbiologically stable during storage at various temperatures. Dermatological tests did not reveal any irritating or allergenic properties. The best data were obtained for the face cream, namely improvement of skin hydration by 21.88%, reduction of transepidermal water loss by 15.86%, alleviation of erythema by 15.77%, and of skin sensitivity by 17.20%. This work resulted in the preparation of innovative dermocosmetics to be used for atopic skin. The cosmetics have a unique composition and delicate formula, show high biofunctionality, and meet all the requirements for cosmetic products intended for marketing.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Biotechnologii i Mikrobiologii Żywności
dc.contributor.authorMatysiak, Joanna
dc.contributor.authorRzetecka, Natalia
dc.contributor.authorKlimczak, Weronika
dc.contributor.authorMichniak-Kohn, Bożena
dc.contributor.authorMatysiak, Jan
dc.contributor.authorSzymanowska, Daria
dc.date.access2024-12-10
dc.date.accessioned2025-01-09T09:33:37Z
dc.date.available2025-01-09T09:33:37Z
dc.date.copyright2023-10-11
dc.date.issued2023
dc.description.abstract<jats:p>Dermocosmetics are products intended for sensitive and problematic skin. They are a good solution for additional care of skin affected by conditions such as atopic dermatitis, acne, psoriasis, or for couperose skin. The compounds of particular importance in the care of atopic skin include ceramides, ectoine, hyaluronic acid, vitamins A and E, as well as natural vegetable oils. The aim of this work was to develop a qualitative and quantitative approach and to investigate the characteristics of formulations such as a face cream, a topical cream, a body lotion, and a cleansing foam, dedicated to patients with atopic dermatitis. The newly developed cosmetic formulations showed good physical and chemical characteristics, typical of this type of product. They were also structurally and microbiologically stable during storage at various temperatures. Dermatological tests did not reveal any irritating or allergenic properties. The best data were obtained for the face cream, namely improvement of skin hydration by 21.88%, reduction of transepidermal water loss by 15.86%, alleviation of erythema by 15.77%, and of skin sensitivity by 17.20%. This work resulted in the preparation of innovative dermocosmetics to be used for atopic skin. The cosmetics have a unique composition and delicate formula, show high biofunctionality, and meet all the requirements for cosmetic products intended for marketing.</jats:p>
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if0,4
dc.description.number4
dc.description.points140
dc.description.versionfinal_published
dc.description.volume80
dc.identifier.doi10.32383/appdr/170202
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/2302
dc.identifier.weblinkhttps://www.ptfarm.pl/wydawnictwa/czasopisma/acta-poloniae-pharmaceutica/110/-/30118
dc.languageen
dc.relation.ispartofActa Poloniae Pharmaceutica - Drug Research
dc.relation.pages573-589
dc.rightsCC-BY-NC
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.endermocosmetics
dc.subject.enatopic dermatitis
dc.subject.eninstrumental tests
dc.subject.endermatological tests
dc.subject.enformulation stability.
dc.titleStudies on the formulation and functionality of an innovative line of topical products for atopic skin
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue4
oaire.citation.volume80