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Current Perspective About the Effect of a Ketogenic Diet on Oxidative Stress – a Review

cris.virtual.author-orcid0000-0001-5324-5982
cris.virtualsource.author-orcidad6302d1-4126-47ee-bfde-d3636e0b6d0a
dc.abstract.enOxidative stress (OS) plays a pivotal role in the development of many diseases. Therefore, many efforts have been undertaken to minimize the consequences of OS or improve antioxidant defence systems. One solution expected to improve redox homeostasis is the ketogenic diet (KD). KD is a low-carbohydrate, high-fat diet leading to a ketosis state. The shift in metabolism occurring in ketosis can affect the reactive oxygen species (ROS)-producing pathways and influence the expression of enzymes involved in redox homeostasis. Therefore, this review summarizes and discusses existing knowledge about KD and ROS homeostasis. The available tools for evaluating OS status are presented, listing their potential and drawbacks. An important aspect is the summary of the current knowledge about the effect of KD on OS conducted in vitro, in vivo, and in clinical trials. Finally, the review addresses future studies needed to understand the connection between KD and OS.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Technologii Żywności Pochodzenia Roślinnego
dc.contributor.authorDrabińska, Natalia
dc.date.access2025-05-12
dc.date.accessioned2025-08-07T12:22:18Z
dc.date.available2025-08-07T12:22:18Z
dc.date.copyright2024-03-07
dc.date.issued2024
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if2,3
dc.description.number1
dc.description.points100
dc.description.versionfinal_published
dc.description.volume74
dc.identifier.doi10.31883/pjfns/185366
dc.identifier.eissn2083-6007
dc.identifier.issn1230-0322
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/4108
dc.identifier.weblinkhttps://journal.pan.olsztyn.pl/Current-Perspective-About-the-Effect-of-a-Ketogenic-Diet-on-Oxidative-Stress-a-Review,185366,0,2.html
dc.languageen
dc.relation.ispartofPolish Journal of Food and Nutrition Sciences
dc.relation.pages92-105
dc.rightsCC-BY-NC-ND
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.enketogenic diet
dc.subject.enoxidative stress
dc.subject.enantioxidant
dc.subject.enoxidation
dc.subject.enlipids
dc.subtypeReviewArticle
dc.titleCurrent Perspective About the Effect of a Ketogenic Diet on Oxidative Stress – a Review
dc.typeJournalArticle
dspace.entity.typePublication