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Influence of supplementation with probiotic bacteria Lactiplantibacillus plantarum and Latilactobacillus curvatus on selected parameters of duodenum iron metabolism in rats on a high-fat, iron-deficient diet

cris.virtual.author-orcid0000-0002-4173-5965
cris.virtual.author-orcid0000-0002-5418-5632
cris.virtual.author-orcid0000-0002-4731-6243
cris.virtual.author-orcid0000-0001-8417-2245
cris.virtual.author-orcid0000-0002-0937-8427
cris.virtualsource.author-orcidc8f75a2c-3403-4f93-aa73-6cf0ae8b543d
cris.virtualsource.author-orcidccd52a90-8355-4384-b6ea-c94578ebf2ce
cris.virtualsource.author-orcidd951fe7e-3886-48a5-8661-b05d0c844622
cris.virtualsource.author-orcidedf63522-bb89-4788-a8d3-9c3f3858875b
cris.virtualsource.author-orcid31a85399-18e5-444d-b0c6-96b441dd2551
dc.abstract.enObjectives: A high-fat, iron (Fe)-deficient Western diet induces obesity and dysregulates Fe metabolism. We compared the influence of Lactiplantibacillus plantarum and Latilactobacillus curvatus with and without Fe supplementation on duodenal Fe uptake under high-fat diet conditions. Methods: Rats were fed a high-fat diet (HF group) or high-fat, Fe-deficient diet (HFDEF group) or control diet (C group) for 8 wk. For the next 8 wk, the rats in the C and HF groups continued on the same diet, whereas the rats in the HFDEF group were divided into six groups and fed high-fat, Fe-deficient diet combinations with L. plantarum (Lp), L. curvatus (Lc), and Fe supplementation (HFDEF, HFDEFFe, HFDEFLp, HFDEFLc, HFDEF FeLp, HFDEFFeLc). Duodenum and serum samples were collected for analysis. Results: In the duodenum, the Fe content was higher in the HFDEFFeLp and HFDEFFeLc groups; the ferropor tin level was higher in the HFDEFFeLp and HFDEFFeLc groups versus the HF group; the divalent metal trans porter 1 level was higher in the HFDEFFeLc group versus the C and HF groups; and duodenal cytochrome B was higher in the HFDEFLc versus all the other groups. In addition, duodenal expression of the solute carrier family 11 member 2 gene washigher in the HFDEF group versus the C, HF, HFDEFFe, HFDEFFeLp, and HFDEF FeLc groups; that of the TFRC gene was higher in the HFDEFFeLc group versus the C, HF, HFDEF, and HFDEFFe groups; and that of the HJV gene was higher in the HFDEFFeLp group versus the C, HF, HFDEF, HFDEFFe, and HFDEFLc groups. Conclusions: L. plantarum and L. curvatus supplementation shows some potential to enhance duodenal cellu lar Fe uptake in rats on a high-fat, Fe-deficient diet.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Żywienia Człowieka i Dietetyki
dc.affiliation.instituteKatedra Biotechnologii i Mikrobiologii Żywności
dc.contributor.authorSkrypnik, Katarzyna
dc.contributor.authorOlejnik-Schmidt, Agnieszka
dc.contributor.authorMikołajczyk-Stecyna, Joanna
dc.contributor.authorSchmidt, Marcin
dc.contributor.authorSuliburska, Joanna
dc.date.access2024-11-07
dc.date.accessioned2024-11-18T10:09:50Z
dc.date.available2024-11-18T10:09:50Z
dc.date.copyright2024-09-30
dc.date.issued2025
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if3,2
dc.description.numberJanuary 2025
dc.description.points140
dc.description.versionfinal_published
dc.description.volume129
dc.identifier.doi10.1016/j.nut.2024.112591
dc.identifier.eissn1873-1244
dc.identifier.issn0899-9007
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/2022
dc.identifier.weblinkhttps://www.sciencedirect.com/science/article/pii/S0899900724002405?via%3Dihub
dc.languageen
dc.relation.ispartofNutrition
dc.relation.pagesart. 112591
dc.rightsCC-BY
dc.sciencecloudsend
dc.subject.enProbiotics
dc.subject.enIron supplementation
dc.subject.enHigh-fat diet
dc.subject.enIron deficiency
dc.subject.enDuodenum
dc.titleInfluence of supplementation with probiotic bacteria Lactiplantibacillus plantarum and Latilactobacillus curvatus on selected parameters of duodenum iron metabolism in rats on a high-fat, iron-deficient diet
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.volume129