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Chapter 10 - Chitosan-based nanoparticles for ocular drug delivery

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cris.virtual.author-orcid0000-0001-9832-9274
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cris.virtualsource.author-orcid36173a57-3417-4bf8-99ea-e027717d422c
dc.abstract.enIn recent years, nanotechnology-based pharmaceutical formulations have gained much importance. It is due to their ability to improve bioavailability at the intended site of action. Improvement in bioavailability can be associated with their ability to proficiently penetrate through tight junctions. Chitosan-based nanoparticulate systems have been extensively and successfully studied in drug delivery and found notable applications in ocular drug delivery. The mucoadhesive property of chitosan improves the ocular residence time of the formulations within the cul-de-sac. An increase in ocular residence time concurrently enhances the transmucosal permeation of the drugs. The current chapter briefly discusses the application of chitosan-based nanoparticles for ocular drug delivery. For a better understanding, the chapter also gives prior knowledge on the anatomy of the eye, different ocular barriers, and the properties of chitosan for ocular drug delivery.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Fizyki i Biofizyki
dc.contributor.authorPal, Kunal
dc.contributor.authorPradhan, Bikash K.
dc.contributor.authorKim, Doman
dc.contributor.authorJarzębski, Maciej
dc.contributor.editorPal, Kunal
dc.contributor.editorVerma, Sarika
dc.contributor.editorDatta, Pallab
dc.contributor.editorBarui, Ananya
dc.contributor.editorHashmi, S.A.R.
dc.contributor.editorSrivastava, Avanish Kumar
dc.date.accessioned2025-12-15T06:38:59Z
dc.date.available2025-12-15T06:38:59Z
dc.date.issued2023
dc.description.bibliographyil., bibliogr.
dc.description.points20
dc.identifier.doi10.1016/B978-0-323-88524-9.00023-1
dc.identifier.isbn978-0-323-88524-9
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/6387
dc.languageen
dc.pubinfoAmsterdam
dc.publisher.ministerialElsevier
dc.relation.bookAdvances in Biomedical Polymers and Composites: Materials and Applications
dc.relation.pages247-263
dc.sciencecloudnosend
dc.subject.enchitosan
dc.subject.ennanoparticle
dc.subject.enocular drug delivery
dc.subject.eneye
dc.titleChapter 10 - Chitosan-based nanoparticles for ocular drug delivery
dc.typeMonographChapter
dspace.entity.typePublication