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Thermo-oxidative stability of asymmetric distigmasterol-modified acylglycerols as novel derivatives of plant sterols

cris.virtual.author-orcid0000-0001-6343-332X
cris.virtual.author-orcid0000-0002-4385-0051
cris.virtual.author-orcid0000-0002-0529-3725
cris.virtual.author-orcid0000-0001-7706-4035
cris.virtual.author-orcid0000-0003-3708-2890
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid307551d0-aa67-4ae6-b57b-fb099d8300e7
cris.virtualsource.author-orcid48ec8e95-930e-4be2-b47a-b597e5d7440b
cris.virtualsource.author-orcida4043375-ad34-47db-b06a-c0b221cf8d5b
cris.virtualsource.author-orcid349c35ce-c6ee-4d8a-9a7f-b3aace65dbd7
cris.virtualsource.author-orcida0e99de6-16e7-4a8e-955e-348a7bec4f41
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.abstract.enThe study investigated the thermo-oxidative stability of distigmasterol-modified acylglycerols as a new structured acylglycerols. Samples were heated at 60 and 180 °C for 8 h. Their percentage degradation and products formed during heating were compared with free stigmasterol and stigmasteryl esters. The remaining of stigmasterol and fatty acid parts, the formation of stigmasterol oxidation products and the composition of polar and non-polar fractions were analysed using chromatographic methods. The cytotoxicity and genotoxicity were determined with the use of an MTT test and a comet assay, respectively. The highest stability during heating was observed for 2,3-distigmasterylsuccinoyl-1-oleoyl-sn-glycerol (dStigS-OA) and the lowest for 2,3-distigmasterylcarbonoyl-1-oleoyl-sn-glycerol (dStigC-OA). Data showed that the formation of thermo-oxidative degradation products is affected by the temperature and chemical structure of lipids present in the molecule. The dStigMAs bonded by a succinate linker and products formed during their thermo-oxidation showed no cytotoxic or genotoxic activity to normal human cells.
dc.affiliationWydział Nauk o Żywności i Żywieniu
dc.affiliation.instituteKatedra Technologii Żywności Pochodzenia Roślinnego
dc.affiliation.instituteKatedra Biotechnologii i Mikrobiologii Żywności
dc.contributor.authorRudzińska, Magdalena
dc.contributor.authorOlejnik, Anna
dc.contributor.authorGrygier, Anna
dc.contributor.authorKowalska, Katarzyna
dc.contributor.authorKmiecik, Dominik
dc.contributor.authorGrudniewska, A.
dc.contributor.authorChojnacka, A.
dc.contributor.authorGładkowski, W.
dc.contributor.authorMaciejewska, G.
dc.contributor.authorPrzybylski, R.
dc.date.access2026-02-16
dc.date.accessioned2026-02-26T13:25:29Z
dc.date.available2026-02-26T13:25:29Z
dc.date.copyright2022-05-06
dc.date.issued2022
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.if8,8
dc.description.number1 October 2022
dc.description.points200
dc.description.versionfinal_published
dc.description.volume390
dc.identifier.doi10.1016/j.foodchem.2022.133150
dc.identifier.issn0308-8146
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/7506
dc.identifier.weblinkhttps://www.sciencedirect.com/science/article/pii/S0308814622011128
dc.languageen
dc.relation.ispartofFood Chemistry
dc.relation.pagesart. 133150
dc.rightsCC-BY
dc.sciencecloudnosend
dc.share.typeOTHER
dc.subject.enstructured lipids
dc.subject.enphytosterols
dc.subject.enacylglycerols
dc.subject.enthermo-oxidative stability
dc.subject.enoxyphytosterols
dc.subject.encytotoxicity
dc.titleThermo-oxidative stability of asymmetric distigmasterol-modified acylglycerols as novel derivatives of plant sterols
dc.typeJournalArticle
dspace.entity.typePublication