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Cornelian cherry fruits as a source of compounds that protect proteins from oxidative stress

cris.virtual.author-orcid0000-0002-9498-819X
cris.virtualsource.author-orcidd9f431b5-a0b9-488d-959c-edc054dfb309
dc.abstract.enIntroduction: Cornelian cherry (Cornus mas L.) fruits are rich in vitamin C, phenolics and other compounds shaping their high antioxidant profile. Natural-based antioxidants may inhibit degradation of pivotal biological macromolecules such as DNA, proteins and molecular membranes. Objective: The study aimed to assess the cornelian cherry extract effect on the inhibition of protein oxidation, which could help limit generation of the advanced oxidation protein products (AOPPs), that are responsible for inflammatory states. Methods: The protective effect was evaluated in in vitro model, in which albumin solution was exposed to oxidation stress in the presence of different doses of C. mas extract. The results were supported by characteristics of the extract under their total phenolic, total flavonoid and vitamin C content. Also, the antioxidant potential was validated using ABTS test (TEAC). Results: Observed was moderate inhibitory effect of the extract and antiradical activity against ABTS. However, both studied effects rather result from other bioactive compounds than the flavonoids. Conclusion: Cornelian cherry fruits has moderate potential to inhibit protein oxidation. However, the observed antioxidant effect rather depends on other compounds than the flavonoids and vitamin C. Nonetheless, the collected results could be helpful in future designing and development of plant-based agents inhibiting the formation of AOPPs.
dc.affiliationWydział Rolnictwa, Ogrodnictwa i Bioinżynierii
dc.affiliation.instituteKatedra Biochemii i Biotechnologii
dc.contributor.authorSzczepaniak, Oskar
dc.date.access2024-11-08
dc.date.accessioned2024-11-08T12:41:44Z
dc.date.available2024-11-08T12:41:44Z
dc.date.copyright2024-06-24
dc.date.issued2024
dc.description.abstract<jats:p>Cornelian cherry fruits are rich in vitamin C, phenolics and other compounds shaping their high antioxidant profile. The study aimed to assess the cornelian cherry extract effect on the inhibition of protein oxidation. Observed was moderate inhibitory effect of the extract and antiradical activity against ABTS. However, both studied effects rather result from other bioactive compounds than the flavonoids.</jats:p>
dc.description.accesstimeat_publication
dc.description.bibliographyil., bibliogr.
dc.description.financepublication_nocost
dc.description.financecost0,00
dc.description.number2
dc.description.points70
dc.description.reviewreview
dc.description.versionfinal_author
dc.description.volume70
dc.identifier.doi10.5604/01.3001.0054.6830
dc.identifier.eissn2449-8343
dc.identifier.issn0018-0599
dc.identifier.urihttps://sciencerep.up.poznan.pl/handle/item/2010
dc.identifier.weblinkhttps://herbapolonica.pl/article/546830/en
dc.languageen
dc.pbn.affiliationfood and nutrition technology
dc.relation.ispartofHerba Polonica
dc.relation.pages121-126
dc.rightsCC-BY-NC-ND
dc.sciencecloudsend
dc.share.typeOPEN_JOURNAL
dc.subject.enCornus mas
dc.subject.enprotein oxidation
dc.subject.enantioxidants
dc.subject.enROS
dc.subject.pldereń jadalny
dc.subject.plutlenianie białek
dc.subject.plantyoksydanty
dc.subject.plROS
dc.subtypeReviewArticle
dc.titleCornelian cherry fruits as a source of compounds that protect proteins from oxidative stress
dc.typeJournalArticle
dspace.entity.typePublication
oaire.citation.issue2
oaire.citation.volume70